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Focus on stroke: Restructuring the brain
The Beano (like The Beezer before it) hypothesises that our perceptions and actions are managed by five little men living in five separate rooms in our skulls. Although modern neuroscience has yet to...
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Focus on stroke: What’s needed for a fitter future?
Provided with permission of the Stroke Association. Copyright: Stroke Association We asked a number of leading clinicians, researchers and other professionals working in stroke the question: With...
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Focus on Stroke
It’s estimated to cost the economy £8 billion per year in England. It causes more than 50 000 deaths every year in the UK and leaves hundreds of thousands more people disabled. A quarter of cases occur...
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Arts, anarchy and cancer: a symposium
Screen grabs of Nick Rothwell’s Voronoi cell systems with tumours growing amidst the organisms and causing systemic collapse. The system is based on venous network geometries supplied by Simon...
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“Three parent” headlines distract from the real issues of mitochondrial...
Three mitochondria surrounded by cytoplasm The Nuffield Council on Bioethics has published a report titled Novel techniques for the prevention of mitochondrial DNA disorders: an ethical review. Geoff...
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Feature: Out of the shadows – freeing families from mitochondrial inherited...
Image: Mitochondria (red) in the cell cytoplasm. Credit: Dr David Furness, Wellcome Images. Mitochondrial inherited diseases (MIDs) can devastate families, but there is hope in the form of new...
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Life as a twin-ea pig: Back to the Twin Research Unit
I fell on the four-finger KitKat like a woman possessed. It was nearly 8 hours since my sister and I had eaten. In the meantime, we’d been scanned, weighed, measured and bled. Never had chocolate...
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Real voices: Ellie Simmonds, Paralympic swimmer
Ellie Simmonds and Oscar Pistorius Later today, British swimmer Ellie Simmonds will attempt to win her second gold medal of the 2012 Paralympics, as she races in the 200m. Here, we meet Ellie and hear...
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Accelerating ageing research
Dr Ilaria Bellantuono of the MRC-Arthritis Research UK Centre for Integrated Research into Musculoskeletal Ageing is one of the founders of ShARM (Shared Ageing Research Models), a new, not-for-profit...
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Beating Diabetes: what can we learn from the SABRE study?
Blood glucose meter The SABRE study has hit the headlines for its research into the high levels of diabetes in minority ethnic communities. The study reveals the extent of ethnic differences in the...
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How your kids might help you in ways you never imagined
We’re publishing the shortlisted entries to the 2012 Wellcome Trust Science Writing Prize. Here, Rhea Chatterjea on how pregnancy doesn’t just take, but gives as well. If you broke your arm when you...
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Sticking points in HIV treatment
‘“Why did you stop taking the drugs?” ‘I tell them, “I have stopped because I don’t have enough food.” Then they say, “You must not stop! […] Eat and take your medicine!” ‘Their thoughts and my...
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Wellcome Image of the Month: Men’s Health
Abnormal human sperm To coincide with ‘Movember’, this month’s focus is on men’s health. Behind the month-long moustache growing event is an important message: to raise awareness of men’s health...
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The Portrait of a Fly (part 1): Come fly with me
For more than a hundred years, scientists have used the fruit fly (Drosophila melanogaster) to study the fundamentals of developmental biology and genetics. But as biological understanding and...
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The Portrait of a Fly (part 2): Fly on the wall
Drosophila: the model model organism; the humble fruit fly with a noble (not to mention Nobel) place in the history of science. Having learned about its importance in genetics and developmental...
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World Cancer Day: Stories from the day hospice
Illustration by Marianne Dear Today is World Cancer Day. This year’s campaign is about dispelling myths around cancer. Chrissie Giles, who ran a creative writing group in a hospice over the summer of...
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Feature: deceptive appearances – engineering cartilage
An illustration of the changes in articular cartilage that occur in osteoarthritis. Credit: Medical Art Service, Munich, Wellcome Images. The tiny area of uncertainty that is inevitably left by...
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One drug, multiple actions
A pill that claimed to target several areas of the body. Drug discovery is a laborious process, often involving a significant degree of trial and error in a medicinal chemistry lab. Historically, many...
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Uncovering the hidden mutations in developmental disorders
Mouse models are teaching us a lot about developmental disorders, but some mutations remain hidden because of their very nature. Tim Mohun explains how a major new genetics project is going to uncover...
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Tubular belle: Q&A with Dr Helen Weavers
In March, Helen Weavers was awarded the 2013 Beddington Medal for the best developmental biology thesis, which she produced at the end of her Trust-funded PhD. I asked her about her research and plans...
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